“We do need some stinkin’ rules”, read the rules and disclaimers.
“Morpheus is considered by many to be the most dangerous man alive.”
Agent Smith from The Matrix
Why are the opiates some of the most highly addictive substances out there? The answer is that your brain and body make these compounds in the form of endorphins and enkephalins. The opiates are chemicals from the opium poppy (papaver somniferum – the poppy that causes sleep), or lab synthesized ones that are structurally similar to them[i]. Their functions are to help kill pain, make us feel good and relaxed, regulate body temperature, water regulation, feeding and stress[ii]. Once you start taking them from an external source, it is very hard to stop using them. Ironically, many of those addicted to opiates become so through legitimate medicine prescriptions for chronic and acute pain. Drugs such as Oxycontin, Oxycodon, Demerol, Codeine, Morphine and Heroin are all opiates and are extensively used in Medicine (with the exception of Heroin).
The opiates also carry the real risk of overdose and death. This happens when people miscalculate the dose due to either an unknown concentration, a relapse at the same dose after a period of abstinence (kicking, then going back at the same level) or chasing the high (that first time is the best one, and many people try more to get to the same feeling- which is impossible by the way). Another way overdose occurs is due to environmental cues. For example, if you always use an opiate in the comfort of your home, at the same dose, then go and use that same dose in an unfamiliar environment, OD may happen[iii]. This probably happens because the anticipation of the drug changes, which increases your endorphins. Add that to the dose of opiate and you might leave this planet (sans body).
Overdose also occurs when you mix your drugs because you weren’t following Abuse rule #10: Don’t mix poisons! (ie: the speedball- cocaine mixed with heroin….FYI…Don’t do this! Remember John Belushi and Philip Seymour Hoffman? That’s what they did and the world was a better place when they were in it making us laugh. It is also a better place with you in it).
So…if dying is something you’d rather not do, this is one plane ride to miss. However, if you’re still reading, let’s mitigate the mayhem.
Naloxone Injection Kit
Naloxone is the injection that will save your life if you overdose (OD). However, in order to get this shot given to you (cuz you will be way too out of it to do it yourself if you OD), there needs to be someone else with you. Which means….drumroll…Don’t use opiates if you are by yourself! You can get Naloxone injection kits from many clean injection sites, from your doctor or public health nurse, and even some outreach programs that dispense them. They are also free, so there is no excuse why you shouldn’t have one. They are also called Narcan kits (US trade name). To use one:
- Draw up 1cc (1ml) of Naloxone in the Intramuscular syringe
- Roll person whom has overdosed on their side
- Inject them either in their thigh, outer ass cheek, or shoulder muscle
- Move out of the way as they will be like a zombie that rapidly wakes up.
- Wait for 10-15 min then hit them with another 1cc (1ml) shot.
Since you will be all panic-y when doing this for the first (and hopefully only) time, don’t worry about swabbing the injection site. Just go through the person’s clothing. The kits generally contain several shots. Make sure that after you have given the shot, you stay with the person and call the ambulance! When the shot wears off, there may be some opiates left in the person’s system, and if it is too much, they will go right back to OD-ing, which means that you’ll have to hit ‘em again with another shot. How do you recognize someone is OD-ing?
- Their lips are blue
- They don’t appear to be breathing
- They are unresponsive and don’t feel pain (try flicking the tip of their nose hard)
- If you peel back their eyelids, they will have pin-point pupils (even in a dark room)
Now for starters, if you are going to use opiates in whatever form, your frequency of use will dictate how fast you become tolerant, then dependent and addicted. You do not want this to happen! If it does, then you will have to eventually go through withdrawal, which SUCKS! In order to prevent this, use opiates (if you’re gonna) no more than 2 times per month. At that frequency, you stand a much better chance of:
- Not getting addicted
- Not fucking up your life
- Not going through withdrawal, which SUCKS!
- Not getting so FUBAR that you are difficult to help by us practitioners
- Not going broke
- Not going to prison
- Not becoming someone’s ‘Prison Bitch’ if you do get sent to the “Big House”
This is what you might feel if you go through withdrawal conventionally:
1st 24 hours:
muscle aches, restlessness, anxiety, eye discharge (excessive tearing),runny nose, excessive sweating, insomnia, excessive yawning
then the real fun begins after 24 hours:
diarrhea, abdominal cramping, goosebumps (cold turkey), nausea, vomiting, dilated pupils and blurred vision, rapid heart beat, high blood pressure.[iv]
The reason why the withdrawal syndrome happens is because all opioids suppress neurotransmission (i.e. they sedate the fuck out of you). This has the effect of causing the body to respond by desensitizing nerves to the drugs. When you stop, the body bounces back and re-sensitizes the nerves (usually a little too quickly), then voila, the above shit[v]. These symptoms usually begin to improve within 72 hours with feeling normal beginning after about 1 week. If above symptoms sounds like a barrel of monkeys, then you must be Bill Murray’s character in the movie Little Shop of Horrors.
One thing that Heroin, Morphine and Codeine all have in common is that they all come from opium, which comes from a poppy (papaver somniferum- aka “the poppy that causes sleep”). So…lets start at the flower and work our way up.
Having been used and cultivated since about 3400 BC by the Sumerians for medical and recreational purposes, opium has been around for a long long time. It has been used as a pain-killer in medicine right from the beginning and is also addictive. The chief alkaloids in opium are morphine, codeine, thebaine (parent compound of Oxycodone and Naltrexone), papaverine (anti-spasmodic, erectile dysfunction treatment) and noscapine (anti-tussive or cough suppressant which also causes nausea).
The British empire in all its glory was built on the Opium trade. Opium is still one of the biggest (and most lucrative) cash crops in the history of civilization.
In Traditional Chinese Medicine, it is known as the herb Ying Su Ke, and belongs to a class of herbs that function as “stabilizers and binders” (Binds up the intestines and stops diarrhea, as well as consolidating Lung Qi or stopping cough). Needless to say, us Chinese Medicine practitioners don’t have prescriptive rights for this bad boy, as I’m sure you’ll understand why.
Routes of Administration
Traditionally, opium was either smoked, or eaten as it still is today. However, you are highly unlikely to come across opium on the street today (unless of course you are in East Asia- excluding Japan and China). The only way you would find it here is if you grew your own poppies, and, as this is not a manual on how to make your own, tough luck.
The chance that you will screw this one up and overdose are high as you will never be sure of the strength (and size) of plant that you are steeping. Therefore, verdict: FUBAR, then ER and possibly a slab in the morgue unless your partners in crime have Naloxone kits.
On the chance you didn’t read the verdict:
- start with 1tsp of crushed poppy straw (dried husks and stems without seeds)
- put in stove top espresso maker
- heat on stove until all water is used
This method will give a small amount of tea that is very bitter and may be very strong (so sweeten it with honey). You may also experience nausea and vomiting on your first try. As you won’t know just how potent the tea is, take only 1/3 of an espresso cup, then wait 25-30min. If you start feeling effects you will have an idea of the dosage. If you feel nothing, increase your dosage by half ad nauseum (pun intended) until you do.
Opium was traditionally smoked via the special pipes pictured below:[vi]
The opium pipe was designed with that special lamp you see (in the center of the picture on the left) that gently heated the opium so that the opiates were vaporized and then inhaled through the pipe. However, chances of you getting a nice pipe, like the ones pictured above, are slim to none unless you have a ton of cash to drop. Using a hash pipe will allow you to get a moderate dose, but that won’t compare to the traditional pipe as the temperature is too high. The closest approximation to the pipe would be to use hot knives (just as if you were smoking hash). As for the dosage, start with a booger sized opium piece. As smoking is the fastest way into the body, you won’t need that many booger sized pieces until you feel it (almost immediately). Stop once you do and wait until the high is gone before having more.
Traditionally known as Laudanum (meaning “something to be praised”) and invented by the English physician Thomas Sydenham, it initially contained: 2oz of strained opium, 1oz of saffron (also a narcotic) and 1/8 fluid oz of both cinnamon and cloves that had been dissolved in a fortified wine known as Canary wine[viii].
Opium tincture is still available today (without the above extra ingredients) and is used in modern medicine to treat explosive diarrhea that doesn’t respond to things like imodium. You have to be reeeal careful should you get your hands on this one though as OD is highly likely if you mess up. Here is how it works:
there are 50drops per ml of standardized tincture.
start dose is 1.5ml (75 drops) better to use a 3ml syringe to measure it.[ix]
If you have never tried it, stick with that dose amigo! It is very bitter, so add it to a cup of whatever you like that is sweet. OD-ing dose is at around 100-150ml for beginners who weigh about 70kg (154lb), although overdoses have been known to occur with half that amount (remember, body weight factors into this, so a small light person will need less to OD). Compared to the insanity of what follows, this is reasonably safe.
Morphine/ Codeine/ Heroin & Methadone etc.
Named after Morpheus, the Greek god of dreams (not The Matrix dude), Morphine is one of the constituents of Opium. It is used extensively in medicine for pain control and finds its way to the street for consumption as well. Standard warnings apply here: (ie: Danger). Some of it’s other street names are: M, Sister Morphine, Vitamin M and Morpho.
Morphine (like Heroin-diacetyl morphine), is very versatile in how it is used. It can be taken orally, sublingually (under the tongue), subcutaneously (aka skin popping), IM (intramuscularly injected- the Keith Richards method), IV (intravenously injected- shooting up), rectally (enema- ew!), intra-nasally (sniffed or sprayed) and dermally (the patch). Anyone can be a saint in the absence of options, which is why you ain’t gonna be one here as there are just too many!
Starting dose: Since most morphine abuse is due to people selling their legitimate prescriptions, there is perhaps less of a likelihood of it being cut with stuff that shouldn’t be there. Also keep in mind that these doses are strictly for non-medical use. Your physician may prescribe different amounts depending on the medical indications they are treating. We are merely trying to prevent you from killing yourself accidentally.
Oral start dose: 10-30mg (immediate release preparations)
Rectal start dose:10-20mg
With these next two methods, you have to do it right otherwise you might be poppy fertilizer. Firstly, DO NOT SHARE NEEDLES! If you do this, you run the risk of getting viruses like Hepatitis and AIDS among others. Use a prepackaged sterile syringe and needle (every time!). Mix the morphine with either distilled water, or physiologic saline (9g salt/liter distilled water) and dilute to 1-2mg/ml of saline solution. Increased concentrations could be painful and cause tissue irritation, and infection.
Intramuscular (I.M.) or Sub-cutaneous start dose: (aka: skin popping) 5-20mg
- Wash hands (see hand washing video)
- Swab area with 70% isopropyl alcohol swab (available at any pharmacy).
- Let air dry
Intra-Muscular (I.M.) Injection Video:
- Angle needle perpendicularly to skin and puncture.
- Draw back slightly to make sure no blood comes into the syringe (if it does, you are in a vein)
- Slowly depress plunger (should take about 30s-3min for entire shot depending on volume)
- For best results use upper outer quadrant of butt cheek (that way you will avoid the sciatic nerve getting injured). Up to 5cc(5ml) per side.
Skin Popping Video:
- Angle needle at about 25 degrees to skin and puncture. (Needle shouldn’t go in more than ½ inch)
- Draw back on needle slightly to make sure no blood comes into the syringe (meaning you are in a vein)
- Slowly depress plunger (should take about 30s-1min for entire shot volume).
- For best results, use upper outer quadrant of butt cheek fat with no more than 1cc(1ml) per site (although can be done anywhere that there is fat tissue)
I.V. (Intravenous) Route:
Just so that you know, this way is the most dangerous method, with venous sclerosis, necrotizing fasciitis, interstitial infiltration (aka. blown veins), thrombosis, collapsed veins, viral infections and abscesses (bacterial infections) as part of the prizes you’ll find behind door number three. Let’s scare you a little more by describing these before getting into the how-to.
Venous Sclerosis- This is where, due to overuse as a result of not rotating injection sites, the veins become hard and difficult to puncture. This can also lead to painful bending of the elbow. Solution: rotate your injection sites.
Necrotizing Fasciitis- Kinda like a flesh eating disease (Staphylococcus Aureas and Streptococcus Pyogenes are the bacterial critters most likely to make a meal out of you). Necrotizing Fasciitis (NF) is where improper hygiene techniques before and during injection procedures were not followed. Basically, you either shared a needle, reused one that wasn’t clean, didn’t prep the skin by swabbing with alcohol, didn’t have gear that was clean or what you injected was contaminated with above mentioned critters. Then…bacterial critters got in there, and then into you, and an infection began. Best-case scenario is that it gets diagnosed quickly and antibiotics are administered and it clears up. However, more often than not, it won’t be and you will end up loosing a limb or a serious amount of tissue cuz the surgeon has to cut it away to stop the spread of infection. FUBAR eh? Solution: watch the safety feature videos that won’t win an Oscar, and use safety procedures.
Gone Interstitial (or blown vein)- This is where you skewer the vein all the way through, or the needle slips out of the vein, or the vein rips and then you yell “FUCK” if the hemorrhaged blood or infusing fluid is too close to a nerve and causes it to be painful. Believe it or not, this is a fairly common mistake that even health professionals make from time to time (as you’ll see in the video). It can leave a nasty-ass bruise and you should withdraw the needle, then apply pressure immediately to the site to minimize this. The size of the needle is also a factor (small gauge is less severe than large gauge- a 30 gauge, ½ inch needle was used in the video). The tourniquet increases the local blood pressure, which can make that bruise so bad. This actually isn’t such a bad complication compared to the other ones and you won’t be able to use the same site for at least 20min. Solution: Be careful, methodical, and mindful and follow the video below (minus the fuck-up at the end). Prayer also helps I hear.
Vein Thrombosis (VT)– basically, it’s a blood clot. A thrombus can occur if there are un-dissolved solids in the solution that you are going to inject. If the clot is big enough, it can travel towards the heart (causing an infarction or heart attack) or the brain (causing a stroke). These thrombi (plural) can also travel around until they get stuck somewhere else and cause a blockage. When this happens it can be very painful (worse than a root canal without anesthesia). Solution: To avoid this, boil a coffee filter in distilled water for 20min (to sterilize it), then take a small piece of boiled filter and draw up your cooked up shot through it. The pores of the filter are not small enough to stop bacteria, but if you sterilize the filter by boiling in distilled water, they won’t be able to cause infection. FYI, if the solution you are going to administer looks really cloudy, that means it has a lot of particulates that haven’t dissolved due to whatever shit they used to cut the drug (therefore, just say no to that shot and find some better smack).
Collapsed Vein– Yup, just what it sounds like. The walls of the vein become irritated and inflamed from too much use, then stick together which blocks off the circulation. This happens if you are using the same vein all the time and re-using needles that are blunt or damaged. This can also happen if you draw back too hard on the plunger to check that you are in the vein. If it does happen:
- withdraw from vein
- apply pressure briefly
- don’t use vein again for a while (1 month)
Generally speaking, the circulation will restore itself. If it doesn’t, the vein resorbs and usually regrows (which takes time). Solution: rotate your injection sites Obi-Wan.
Viral Infections- Yes the ultimate proof that size does not matter! Viruses are tiny things you will never see with the naked eye (hell, bacteria are hard enough to see with a microscope!). So what prized viruses can you expect to win behind this door? How do AIDS, Hepatitis A,B,C and D sound? Solution: NEVER SHARE GEAR! And ALWAYS use new gear with each shot! (THAT INCLUDES THE SPOONS!)
Either boil them (spoons) for 20min then soak in 3% hydrogen peroxide, or Lugol’s Iodine solution (5 drops in ½ cup of sterile or distilled water) and soak the boiled spoon for minimum 10 min! Alternatively, wash the spoon well in soapy water, then put it in a toaster oven for 6 min at 375°F (190°C), then let it cool.
Abscesses (infection)- The ugliest of the ugly. Abscesses are where the injection site gets contaminated with bacteria because you didn’t use the safety precautions outlined above. As a consequence, you get a big swollen, hot, painful, goose-egg-like sore (that kind of looks like a big zit) and is quite noticeable within 24 hours of the injection. Don’t think that it’ll just heal up on its own young Skywalker. This one needs medical attention ASAFP (As Soon As Fucking Possible-in case you were wondering). This is also a big reason why people loose limbs or the infection goes systemic and they die. When you go to Emerg, pray that you get a nice, well-rested doctor on duty. He/ She’ll probably try to numb it before cutting it open and squeezing the zit until the blood no longer has a putrid smell and color. However, it is sometimes tricky to numb these suckers, which means, you will utter lots of high-volume foul language as a means of pain control (assuming that you don’t faint). Then, it will usually be followed up with oral antibiotics (which you must take as directed) to prevent any further infection.
Intravenous (I.V.) 2.5-10mg inject very slowly (up to 1min/cc)
From the Greek word Kodeia or “Poppy Head”, codeine is a weaker opiate alkaloid found in opium gum and the poppy straw of the plant. It makes up about 4-23% of the opioids found in the poppy head. Although it has some analgesic (pain killing) aspects, it is used more for its antitussive (cough stopping) properties, which I’ll wager are not what you are thinking about.
Oral start dose: 15-60mg (of immediate release pills): 50mg (of extended release tablets)
*Note* Don’t crush these or crunch them up as overdose could occur!
Effects start at ½-1hour after taking them and the peak effects occur between 1-1½ hrs.
As there isn’t any other way to take these lets move on shall we.
Heroin…Not the Xena Warrior Princess type
AKA smack, black, tar and horse. Believe it or not, “Heroin” was the marketing trade-name that Bayer (yup, those aspirin pushers) came up with to sell their new ‘non-addictive’ cough suppressant product instead of Morphine back in 1898.[x] I kid you not! (I can’t make this shit up!). Essentially, they just took morphine and reacted it with acetic anhydride, to produce Diacetyl-morphine. Presto! The problem was, it was just as addictive, even faster acting and 1½ – 2 times as strong as morphine.
Because it is stronger, you’re gonna use less unless (in the immortal words of Shakespeare) you wish it to “make worms meat of you” (ie: kill you via OD). Also remember that street heroin is of unknown purity. The concentration can be anywhere from 30-60% pure. Therefore you won’t know what you’ve got until its in you and too late, so… start with the lower end doses to begin with. “Better a small high than die”.
Although this is a relatively uncommon method of use, its best to use half the start dose compared to morphine. Start dose: 5-15mg (for beginners), then wait 25-30min for the effects.
Same applies here. Half the dosage, then wait for the effect. There is a higher absorption with rectal administration as you bypass the digestive system. Start dose: 5-10mg
Intramuscular (I.M.) and Subcutaneous (Skin Popping)
Half here too. Follow the same safety procedures as above. Start Dose: 2.5-8mg
Half the morphine amount, cowboy/girl. Start Dose: 1-5mg
Smoking (Chasing the Dragon) aka: Cheeb
This method is safer than the injection route, but there will be the complications associated with smoking and cutting agents (whatever they might be), namely, lung irritation and pathologies (chronic cough and bronchitis, respiratory infections, and smoking induced asthma). Although the typical method is to take a small chunk (about 0.25g) of black tar heroin and put on a small square of aluminum foil, heat the foil with a lighter and inhale the vaporizing fumes as the heroin boils, there is a better way Obi-Wan. Simply do the Hot –Knife thing that was explained earlier in the opium section. Start Dose: As with Opium, roll a few pieces (the size of small boogers- I know, I’m still struggling with finding a better description) and vaporize them between the hot knives then stop when you feel the effects and don’t have more until a separate occasion. [xi]
According to the CDC (Center for Drug Control- “the Man”), there are about 5000 deaths due to accidents using this little puppy per year. Methadone is most often used as a way to wean people addicted to the above stuff in drug rehab programs. In Russia though, they take the tough love approach and make you do cold turkey without this and simply give you sedatives and NSAIDs like aspirin and ibuprofen to take the edge off. That said, methadone ain’t really a drug of abuse per se. Both oral and IV routes have similar absorption characteristics and shooting provides no rush so why bother. Another thing about methadone is that it is long acting and if you are on a reduction/ maintenance program and you decide to go and do some smack, you will most likely OD and be pushing up poppies in the cemetery from 6 feet under. Verdict: lame, seek life elsewhere. Should you get crazy with the above stuff, methadone substitution is what you will go through to get off them. If you choose to forgo methadone and just get the withdrawal over and done with, a special vitamin cocktail called a Meyers cocktail will minimize the discomfort, which we’ll talk about below.
Speaking of lethal, this little piece of a patch has that in spades. Fentanyl patches are prescribed for intolerable chronic pain (usually associated with cancer). These patches are about 80-100 times more potent than morphine, and 40-50 times more potent than 100% pure heroin (aka “pharmaceutical grade”). When people get their hands on these patches (even when they are used or discarded by folks with prescriptions) they tend to, either eat them (gross!), or scrape then smoke them. There is an epidemic of fatalities due to overdoses as a result. There is also an epidemic of illegal Fentanyl making its way onto the streets in both powdered form, as well as in pills (both of these can be mixed with heroin). THERE IS NO SAFE DOSE. Abuse Rules 2 & 3 apply here (2. Know what you have, 3. Know your starting dose). Since you won’t know either of these, DON’T use Fentanyl. If you feel the need to disregard the above advice, make sure you have a buddy with the Naloxone injection kit, who knows how to use it handy, as you will most likely OD. Field trips to the morgue ain’t cool.
You obviously want to keep your job right? So how do you make sure that you won’t get caught? Well, the first thing to remember is that most urine tests won’t be able to get any detected opiates or metabolites after about 4 days. But that is just piss! There are also the hair tests. These can detect up to 90 days! The only way around detection here is…after the 5 day safety period for urine, shave off all your hair (body as well as head- yes that means a Brazilian as well), then tell the person who would have taken that hair that you lost it all in a bet or due to vitiligo (a disease where one of the symptoms is complete hair loss that is either temporary or permanent). These tests generally come from the Substance Abuse and Mental Health Services Administration (SAMHSA) and the National Institute of Drug Abuse (NIDA). There is a threshold cutoff that is generally observed with these tests. Anything that tests out at 300 ng (nanograms)/ml is considered false positive due to something known as “The Poppy Seed Defense” (ie: someone who likes poppy seed buns a lot could test that high).[xii] The usage cutoff level is 2000ng/ml. At or beyond this level and you are hooped as far as testing goes (you won’t be able to use the “foodie defense”).
There are also a few false positive possibilities that you should be aware of:
Quinolone antibiotics such as: Levofloxacin, Ofloxacin, Perfloxacin and Enoxacin (as well as a few others) can cause false positives.[xiii]
Cough medicines with Dextromethorphan (DXM) or codeine, prescription narcotic painkillers can cause false positives.
If you have diabetes, kidney or liver disease you can have a false positive.
Wow! There was a lot to that section right? That’s due to how dangerous this class of substances is. So now let’s go to the cleaners. Firstly, if you use any of the substances at a frequency of twice per month, you’re unlikely to become habituated (remember Abuse Rule #7: Ritualize your consumption). However, if you strayed to the dark side, lets get you back in the sun.
This truly sucks and is best attempted with supervision by a knowledgeable medical professional. If you have gone to a detox and rehab facility, they will help you through withdrawal. If you choose to do it outside this facility, I would still recommend you to get your family physician on board as they are an essential part of recovery in the long term. Should you not have one, and are “going it alone”, there are some things that you will need to know. Firstly, although opiate withdrawal is very unpleasant, it is seldom fatal (it just SUCKS!).
Why does the withdrawal syndrome work the way it does? Well young paduwan, have you ever heard the expression “What the Sith-lord giveth, he also taketh away”? Same goes here. Opiates cause things to happen, so, their absence causes the reverse to happen. The following chart illustrates this best[xiv]:
|Analgesia (pain relief) good
Respiratory depression not good
Euphoria oh yeah!
Relaxation & Sleep good
Decreased blood pressure good & bad
Pinpoint pupils so-so
Drying of mucus membranes bad
Reduced sex drive very bad
Flushed & warm skin good?
|Pain & irritability FUBAR!
Panting & yawning Hmmm
Dysphoria & depression FUBAR!
Restlessness & insomnia FUBAR!
Fearfulness & hostility FUBAR!
Increased blood pressure bad
Diarrhea Major FUBAR!
Pupil dilation so-so
Tearing & runny nose like a fountain
Spontaneous ejaculation could be good
Chills & goosebumps a la cold turkey
As you can see, not the biggest barrel of monkeys. However, if you want to minimize the withdrawal symptoms there are a few things that you can do to achieve this via vitamin cocktails.
Invented by the late physician John Myers, the “cocktail” is essentially an I.V. infusion given over several minutes that contains the following:
Magnesium Chloride Hexahydrate 20% (magnesium) 2-5ml
Calcium Gluconate 10% (calcium) 1-3ml
Hydroxocobalamin 1000 μg/ml (vitamin B12) 1ml
Pyridoxine Hydrochloride 100mg/ml (vitamin B6) 1ml
Dexpanthenol 250mg/ml (vitamin B5- Pantothenic Acid) 1ml
B Complex 100 (B complex vitamins) 1ml
Contains: Vitamin(B1) Thiamine 100mg
Vitamin(B3) Niacinamide 100mg
Vitamin(B2) Riboflavin 2mg
Vitamin(B5) Dexpanthenol 2mg
Vitamin(B6) Pyridoxine 2mg
Vitamin C 222mg/ml 4-20ml
Sterile Water 8-30ml
The solution is drawn up in one big syringe, then mixed by turning the syringe a few times. It is then administered using a butterfly needle (25 gauge) over the course of 5-15min slowly. The above doses are adult doses and the amounts in the dose vary according to the individual (those who are weak or frail will get less).[xv] The sterile water addition helps to make the hypertonicity of the solution less (which means you won’t feel a burning as it is infused). For even better results, if the physician adds enough sterile water to bring the solution up to 60ml, it is generally well tolerated by everyone. Don’t DIY it here! You can only get these ingredients for injection at a compounding pharmacist.
If you want to get this done, there is a list of physicians in the appendix that are familiar with these. If you don’t have access to one of these people, any physician can make this up and administer it (you just have to ask-nicely if possible).
Typically, you’ll need about 3 of these spaced 1-day apart for the first 3 days during withdrawal and that will allow for minimal discomfort. You may need more though. The cost of the Myers Cocktail varies between $50-$100/ treatment.
Let’s say that you don’t have any access to a Doc. If that happens and you want to quit, start taking the vitamins orally as follows for 1-2days before the start of withdrawal through to the end of it:
Vitamin C 1000mg (6x per day of Lipospheric form) or (1000mg/ hr of ascorbic acid powder) see appendix 2
B complex 3 capsules/day
Magnesium Citrate (1000mg morning, 1000mg night)
Calcium Citrate (500mg morning, 500mg night)
Vitamin B12 (2000 μg/day)
Vitamin B3 (Niacinamide form) (100-500mg/day)
Vitamin B5 (250mg/day)
And plenty of water, as well as Gatorade.
If that were all to it, life would be easy right? Well, since it ain’t easy, neither is this. Opiate addiction also usually causes an imbalance in brain neurotransmitters that will have to be addressed. The endorphin/ enkephalin section in the OrthoHOD App is the most usual area that goes part and parcel with opiate use, and the amino acids in this section will help your brain to replenish it’s balance of neurotransmitters. In addition, diet also matters. Ya gotta eat! What is best to eat will be covered in the diet section. However, what is best not to eat would be fast food (of any variety), and junk food (of any variety). Get a good cookbook (also listed in the food section), and cook your way through it.
Yer also gonna have to bite the bullet once withdrawal is over and get some counseling as there is always a reason why this shit got out of control and a good counselor will be able to help you process it. Suffice it to say that social re-integration is what is key to staying clean.
Very recently, a physician in Perth, Australia by the name of O’Neil has been working to treat addictions by developing a small implant that releases Naltrexone continuously. In high dose Naltrexone/Naloxone are drugs that are given to counter the effects of opiates when an overdose occurs. The problem with high dose is that it immediately starts withdrawal (which SUCKS). The implanted low sustained dose however is yet another ingenious tool, that if used in conjunction with the nutritional protocols mentioned above will not only help brain chemistry to normalize, but also remove the temptation to resume opiate use by blocking their effects. At this time, the FDA has still not approved this device despite the positive results.[xvi]
The ins and outs of Ibogaine are explained in the hallucinogens section (to follow). Ibogaine is an alkaloid from a west African plant that helps people to withdraw from a variety of drugs, but especially opiates.
Kratom leaf comes from a tree that is a member of the coffee family of plants, which comes from Southeast Asia and has been used as both a stimulant (at low to moderate dose) and sedative (at higher dose). It shares a lot in common with opiates, as well as similar chemistry. In Asia, it is used predominantly by farmers and day laborers to “take the edge off” the rigors of hard labor, and muscle pain[xvii]. However, it is less potent than the opiates. As with all traditional herbs that have been beneficial over the centuries of our existence, we in the West decided to say “fuck all that” and find new and interesting ways to abuse it without context. Many a punter have taken it into their heads that they can use this plant for opiate withdrawal as a mono-therapy. The problem with this being that it is also abuse-able, and withdrawal entails similar symptoms that opiate withdrawal has[xviii]. Typical doses used on the low end for mild stimulant activity are between 1-5g of powdered dry plant, and 5-15g for sedative effects. Although it is still legal in North America, that might soon change, based on the paranoia of right leaning governments. If you are planning on using it for withdrawal, it would be better if you combined it with some of the other tools mentioned here instead of just by itself. Should ye be seeking minor buzz, observe all abuse rules (1-11) and don’t use it more than one time per week.
While we are at it, did I mention that acupuncture is also useful at easing the anxiety and promoting the wellness that you shelved when the shit got out of control? It does this by up-regulating your endorphins and internal cannabinoid systems.
A Final Request
After now having provided you with the know-how on needle lore, we request ONE very important thing. PLEASE dispose of your needles in a proper sharps container (which can be obtained free at any pharmacy), then, when it gets full, drop it off at a pharmacy for safe disposal. Don’t be lazy and chuck your used gear in the park, where some 10 year old kid and their dog, can accidentally skewer themselves and be the recipient of any infection that you may be carrying. Also, don’t just chuck it in the garbage where a garbage collector can suffer the same fate. Self-abuse shouldn’t harm others (so don’t be like those NRA twits who advocate for everyone to own firearms, including teachers in schools).
Okay people, opiates are great substances for relieving pain, and when used properly have been one of the greatest god-sends this world has seen. What can be more wonderful than having a substance that gets rid of the scourge of physical suffering? Well we humans have a way of taking something good and making it bad and the story of the opiates is a case in point. At some point, pain must be overcome mentally as well as physically and here nothing of the physical realm helps. It is a change in the way we perceive the pain that changes our relationship to it. And when pain is a symptom of an underlying hurt…well that’s where the road to addiction starts. The mask wearer doesn’t see the mask and thus doesn’t want to remove it, and so, begins believing it’s the mask that needs attention. Which is to say, if you’re using opiates to treat pain, find a compassionate physician to help you evaluate the pain. If there are other methods, in the long run you will be better off; if nothing else but opiates work, someone knowledgeable helping you manage this rocky road is a salve beyond compare.
[i] Ibid Meyer, J S et al. p.312.
[ii] Ibid Meyer, J S et al. p.315.
[iii] Ibid Meyer, J S et al. p.326.
[iv] Opiate withdrawal symptoms., www.healthline.com., retrieved July 9, 2014.
[v] Ibid Meyer, J S et al. p.330.
[vi] Steven Martin. (June, 2007),. Opium Layout photo., Wikimedia Commons.
[vii] Opium Pipe Photo by Steven Martin., Public Domain photograph retrieved from Wikipedia on July 15, 2014.
[viii] Ibid Meyer, J S et al. p.306.
[ix] Wilbur l. Scoville,, Justin L. Powers., (1937) The Art of Compounding., 6th Ed., p.18, Blakiston’s Son & Co. inc., Philadelphia.
[x] Richard Askwith., (1998). “How Aspirin turned Hero” Sunday Times., September 13, 1998., opioids.com
[xi] Robby. “Chasing the Dragon: An Experience with Heroin (Black Tar) (ID 61979)”. Erowid.org. Oct 27, 2007. Erowid.org/exp/61979
[xii] Claire Meadway, Steve George, Robin Braithwaite (1998)., “Opiate concentrations following the ingestion of poppy seed products – evidence for ‘the poppy seed defense’”., Forensic Science International 96 (1998) 29-38.
40 Baden LR, Horowitz G, Jacoby H, Eliopoulos GM (2001)., “Quinolones and false-positive urine screening for opiates by immunoassay technology”., JAMA; 286(24):3115-9.
[xiv] Ibid. Meyer, J S et al. p.326.
[xv] Ibid., Gaby. p. 1295, 1298.
[xvi] Hulse, Gary K., Morris, Noella, Arnold-Reed, Diane, Tait, Robert J. (Oct. 2009). “Improving clinical outcomes in treating heroin dependence: randomized, controlled trial of oral or implant Naltrexone”. Archives of General Psychiatry 66(10): 1108-1115. Doi:10.1001/archgenpsychiatry.2009.130. PMID 19805701.
[xvii] Cinosi E, Martinotti G, Simonato P, Singh D, Demetrovics Z, Roman-Urrestarazu A, Bersani F S, Vicknasingam B, Piazzon G, Li J, Yu W, Kapitány-Fövény M, Farkas J, Giannantonio M, and Corazza O, (2015), Following (the Roots) of Kratom (Mitragyna speciosa):The Evolution of an Enhancer from a Traditional Use to Increase Work and Productivity in Southeast Asia to a Recreational Psychoactive Drug in Western Countries. Hindawi Publishing Corporation BioMed Research International Volume 2015, Article ID 968786, http://dx.doi.org/10.1155/2015/968786.
[xviii] Warner M L,Kaufman N C & Grundmann O., (2016), The pharmacology and toxicology of kratom: from traditional herb to drug of abuse., Int J Legal Med (2016) 130:127–138., DOI 10.1007/s00414-015-1279-y.
Kratom Photo by Uomo vitruviano – Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=12196426